IPPRA / Grant Monitor

2026-07-07
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High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)

RFA-DA-25-060 · National Institutes of Health

biomedical clinical public health mental behavioral health social services Education Health

Closes
2027-03-05 · 241 d
Award ceiling
$1,500,000
Award floor
Program funding
Expected awards
Cost sharing
No
Posted
2024-01-17
Instrument
Grant
Characterization · gpt-5.4-mini · 2026-07-07

NIH will fund high-priority HIV research projects at the intersection of HIV and substance use, across the full spectrum from basic science to clinical and implementation studies, for eligible U.S. and certain other organizations.

Funds
applied research
University
direct
social behavioral
substantial
physical sciences
minor
engineering
minor
life biomedical
central
computational data
substantial

⚑ RM1/Clinical Trial Optional · preliminary data required · must address HIV/AIDS Research Priorities and the nexus with substance use · foreign organizations listed as eligible; non-domestic components of U.S. organizations are not eligible; foreign components allowed

Unit fits — one characterization, each unit's own rules

Physical Sciences & Engineering (demo) 70 strong technical depth: substantial; funds applied research
IPPRA 58 good peripheral portfolio topic: public_health; signature methods: community engaged; social/behavioral work is substantial; funds applied research; biomedical core — IPPRA health lane is communication/crisis/policy (capped); clinical-trial/biomedical core — IPPRA angle is policy/community (capped)
Tom Love Innovation Hub 30 weak funds applied research; deep-tech content

Description

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and substance use. This FOA invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). Applications submitted under this FOA are required to have a detailed research plan, preliminary data, and a clear description of the nexus with substance use. This FOA is open to both individual researchers and research teams and includes all areas of research from basic science to clinical and implementation research. All studies must focus on NIH HIV/AIDS Research Priorities: NOT-OD-20-018: UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding.

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Apply

View on Grants.gov → CONTACT: National Institutes of Health <grantsinfo@nih.gov>

Proposal brief SEE AN EXAMPLE →

A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.

ONE LLM CALL (~1¢) · CACHED · REQUIRES STAFF KEY

Proposal shell · National Institutes of Health conventions SEE AN NIH EXAMPLE →

Funder-faithful document skeletons — National Institutes of Health's document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.

ONE LLM CALL (~2-3¢) · CACHED · SCAFFOLDING, NOT GHOSTWRITING