Natural Product Multi-Site Clinical Trial Data Coordinating Center (Collaborative U24 Clinical Trial Required)
NIH/NCCIH funds a collaborating Data Coordinating Center to provide project coordination, data management, and biostatistical support for a simultaneously submitted investigator-initiated multi-site Phase III-or-later natural products clinical trial.
⚑ Must be submitted simultaneously with the corresponding CCC application under TEMP-26943. · Clinical trial required; DCC must be specific to the paired trial. · Foreign organizations are listed as eligible, but non-domestic components of U.S. organizations are not eligible. · Applicants are strongly encouraged to contact the Scientific/Research contact before submission.
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 90 strong | technical depth: central; funds data infrastructure |
| IPPRA | 58 good | portfolio topic: public_health; social/behavioral work is minor; funds data/survey infrastructure; clinical-trial/biomedical core — IPPRA angle is policy/community (capped) |
| Tom Love Innovation Hub | 15 none | deep-tech content; no commercialization signal |
Description
This Notice of Funding Opportunity (NOFO), utilizing the U24 grant funding mechanism, encourages applications for a collaborating Data Coordinating Center (DCC) application that accompanies an investigator-initiated multi-site clinical trial (Phase Ill and beyond) application submitted underTEMP-26943. The DCC application must be specific to the collaborating Clinical Coordinating Center (CCC) application. The objective of the DCC application is to propose a comprehensive plan that provides overall project coordination, and administrative, data management, and biostatistical support for the proposed clinical trial. Both a DCC application and a corresponding CCC application need to be submitted simultaneously for consideration by NCCIH. Trials for which this NOFO applies must be relevant to the research mission of the NCCIH and considered a high priority by the Center. For additional information about the mission, strategic vision, and research priorities of the NCCIH, applicants are encouraged to consult the NCCIH website: (http://www.nccih.nih.gov). Applicants are strongly encouraged to contact the appropriate Scientific/Research contact for the area of science for which they are planning to develop an application prior to submitting to this NOFO.
Eligibility
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Apply
View on Grants.gov → CONTACT: National Institutes of Health <grantsinfo@nih.gov>
Proposal brief
Proposal shell · National Institutes of Health conventions
Legacy IPPRA LLM assessment (v2.0, for comparison)
10/100 · gpt-5.4-mini · 2026-07-06
This is a clinical-trial Data Coordinating Center opportunity for NCCIH natural product studies, focused on project coordination, data management, and biostatistics rather than IPPRA’s core behavioral, policy, or community-facing research niches. While it sits in public health, it does not center on health communication, crisis response, or social/behavioral research, so the fit is weak. Public universities are eligible, but IPPRA would more likely be a support partner than a lead research anchor.
Legacy scoring history
| 2026-07-06 | 10 | gpt-5.4-mini | This is a clinical-trial Data Coordinating Center opportunity for NCCIH natural product studies, focused on project coordination, data management, and biostatistics rather than IPPRA’s core behavioral, policy, or community-facing research niches. While it sits in public health, it does not center on health communication, crisis response, or social/behavioral research, so the fit is weak. Public universities are eligible, but IPPRA would more likely be a support partner than a lead research anchor. |
| 2026-07-06 | 14 | gpt-5.4-mini | This is an NIH cooperative agreement for a data coordinating center supporting natural product clinical trials, which is predominantly biomedical and trial-infrastructure oriented rather than aligned with IPPRA’s social science, policy, or risk-communication strengths. IPPRA could potentially contribute only in a limited ancillary role on participant behavior or communication, but the opportunity is not centered on those dimensions. Public universities appear eligible, so the score is not capped for ineligibility. |