IPPRA / Grant Monitor

2026-07-07
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Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)

PAR-25-255 · National Institutes of Health

biomedical clinical ai data science public health social services Education Health

Closes
2026-11-05 · 121 d
Award ceiling
Award floor
Program funding
Expected awards
Cost sharing
No
Posted
2024-11-15
Instrument
Grant
Characterization · gpt-5.4-mini · 2026-07-07

Supports interdisciplinary R01 projects that develop new theory and methods to understand how genetic and non-genetic factors shape variation in complex human traits using modeling and validation with large-scale datasets.

Funds
basic research
University
direct
social behavioral
substantial
physical sciences
minor
engineering
minor
life biomedical
central
computational data
central

⚑ R01 Clinical Trial Not Allowed · foreign organizations are eligible · open to many institution types including MSIs, tribal colleges, faith-based/community-based organizations, and U.S. territorial entities

Unit fits — one characterization, each unit's own rules

Physical Sciences & Engineering (demo) 90 strong technical depth: central; funds basic research
IPPRA 84 strong portfolio topic: public_health; social/behavioral work is substantial; funds basic research
Tom Love Innovation Hub 15 none deep-tech content; no commercialization signal

Description

The goal of this NOFO is to support applications for novel theory and methods development that enable better understanding of how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary drawing from the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, modeling, and validation with available large-scale datasets.

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Apply

View on Grants.gov → CONTACT: National Institutes of Health <grantsinfo@nih.gov>

Proposal brief

ONE LLM CALL (~1¢) · CACHED · REQUIRES STAFF KEY

Proposal shell · National Institutes of Health conventions

ONE LLM CALL (~2-3¢) · CACHED · SCAFFOLDING, NOT GHOSTWRITING