IPPRA / Grant Monitor

2026-07-07
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Schizophrenia and related disorders during mid- to late-life (R21 Clinical Trial Optional)

PAR-25-040 · National Institutes of Health

biomedical clinical mental behavioral health public health ai data science Health

Closes
2026-09-07 · 62 d
Award ceiling
Award floor
Program funding
Expected awards
Cost sharing
No
Posted
2024-11-18
Instrument
Grant
Characterization · gpt-5.4-mini · 2026-07-07

R21 grants supporting translational research on the emergence and course of schizophrenia and related disorders in mid- to late-life, including identification of prevention and treatment targets.

Funds
applied research
University
direct
social behavioral
substantial
life biomedical
central
computational data
substantial

⚑ R21 Clinical Trial Optional; clinical trials may be included but are not required. · No explicit U.S.-only restriction; foreign organizations are listed as eligible. · Standard NIH grant application rules apply; award ceiling shown as $0 in the notice metadata.

Unit fits — one characterization, each unit's own rules

Physical Sciences & Engineering (demo) 80 strong technical depth: substantial; funds applied research
IPPRA 58 good portfolio topics: mental_behavioral_health, public_health; social/behavioral work is substantial; funds applied research; clinical-trial/biomedical core — IPPRA angle is policy/community (capped)
Tom Love Innovation Hub 30 weak funds applied research; deep-tech content

Description

Although the majority living with schizophrenia and related disorders are over 35 years old, including those first diagnosed and those aging with the illness, the mechanisms underlying the generation and trajectory of the illness remain poorly understood. The purpose of this initiative is to advance translational research to better understand the emergence and trajectory of schizophrenia and related disorders in mid to late life, and to identity targets for future development of prevention and treatment efforts.

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Apply

View on Grants.gov → CONTACT: National Institutes of Health <grantsinfo@nih.gov>

Proposal brief

ONE LLM CALL (~1¢) · CACHED · REQUIRES STAFF KEY

Proposal shell · National Institutes of Health conventions

ONE LLM CALL (~2-3¢) · CACHED · SCAFFOLDING, NOT GHOSTWRITING