Schizophrenia and related disorders during mid- to late-life (R21 Clinical Trial Optional)
R21 grants supporting translational research on the emergence and course of schizophrenia and related disorders in mid- to late-life, including identification of prevention and treatment targets.
⚑ R21 Clinical Trial Optional; clinical trials may be included but are not required. · No explicit U.S.-only restriction; foreign organizations are listed as eligible. · Standard NIH grant application rules apply; award ceiling shown as $0 in the notice metadata.
This is a biomedical/clinical mental health R21 on schizophrenia mechanisms and translational prevention/treatment, which is far outside IPPRA’s social-behavioral risk, communication, and policy portfolio. The team could not plausibly pursue this as PI-level work except at a very general public-health-adjacent level.
JUDGED AGAINST THE ROSTER'S PUBLICATION DOSSIER · GPT-5.4-MINI · 2026-07-07
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 80 strong | technical depth: substantial; funds applied research |
| IPPRA | 58 good | peripheral portfolio topic: public_health; social/behavioral work is substantial; funds applied research; biomedical core — IPPRA health lane is communication/crisis/policy (capped); clinical-trial/biomedical core — IPPRA angle is policy/community (capped) |
| Tom Love Innovation Hub | 30 weak | funds applied research; deep-tech content |
Description
Although the majority living with schizophrenia and related disorders are over 35 years old, including those first diagnosed and those aging with the illness, the mechanisms underlying the generation and trajectory of the illness remain poorly understood. The purpose of this initiative is to advance translational research to better understand the emergence and trajectory of schizophrenia and related disorders in mid to late life, and to identity targets for future development of prevention and treatment efforts.
Eligibility
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Apply
View on Grants.gov → CONTACT: National Institutes of Health <grantsinfo@nih.gov>
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