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2026-07-07
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Investigator Initiated Innovation in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)

PAR-25-228 · National Institutes of Health

ai data science biomedical clinical computing communications public health Education Health

Closes
2027-09-07 · 427 d
Award ceiling
Award floor
Program funding
Expected awards
Cost sharing
No
Posted
2024-11-18
Instrument
Grant
Characterization · gpt-5.4-mini · 2026-07-07

NIH supports investigator-initiated research developing scalable computational genomics, data science, statistics, and bioinformatics methods, tools, and software for broad use in human genomic science and health, with no clinical trials allowed.

Funds
basic research
University
direct
social behavioral
minor
physical sciences
minor
engineering
substantial
life biomedical
central
computational data
central

⚑ R01; Clinical Trial Not Allowed · broadly open eligibility including foreign organizations and many minority-serving/tribal/territorial categories · focus must be enabling/generalizable across diseases and biological systems · applications must address scalability to larger datasets

Unit fits — one characterization, each unit's own rules

Physical Sciences & Engineering (demo) 90 strong technical depth: central; funds basic research
IPPRA 58 good peripheral portfolio topic: public_health; social/behavioral work is minor; funds basic research; biomedical core — IPPRA health lane is communication/crisis/policy (capped)
Tom Love Innovation Hub 30 weak prototyping/demonstration stage; deep-tech content

Description

The purpose of this funding opportunity announcement (FOA) is to invite applications for a broad range of research efforts in computational genomics, data science, statistics, and bioinformatics relevant to one or both of basic or clinical genomic science, and broadly applicable to human health and disease. This FOA supports fundamental genomics research developing innovative analytical methodologies and approaches, early-stage development of tools and software, and refinement or hardening of software and tools of high value to the biomedical genomics community. Work supported under this FOA should be enabling for genomics and be generalizable or broadly applicable across diseases and biological systems. All applications should address how the methods would scale to address increasingly larger data sets.

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Apply

View on Grants.gov → CONTACT: National Institutes of Health <grantsinfo@nih.gov>

Proposal brief SEE AN EXAMPLE →

A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.

ONE LLM CALL (~1¢) · CACHED · REQUIRES STAFF KEY

Proposal shell · National Institutes of Health conventions SEE AN NIH EXAMPLE →

Funder-faithful document skeletons — National Institutes of Health's document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.

ONE LLM CALL (~2-3¢) · CACHED · SCAFFOLDING, NOT GHOSTWRITING