IPPRA / Grant Monitor

2026-07-07
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Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R01 Clinical Trial Optional)

PAR-25-065 · National Institutes of Health

biomedical clinical mental behavioral health ai data science Health

Closes
2026-09-07 · 62 d
Award ceiling
Award floor
Program funding
Expected awards
Cost sharing
No
Posted
2024-11-18
Instrument
Grant
Characterization · gpt-5.4-mini · 2026-07-07

R01 research grants are funded to study biological and biobehavioral mechanisms underlying neuropsychiatric symptoms in Alzheimer’s disease or related dementias, with clinical trials optional.

Funds
basic research
University
direct
social behavioral
substantial
life biomedical
central
computational data
substantial

⚑ R01; clinical trials optional · Foreign organizations and several non-university applicant classes are explicitly eligible · Award ceiling listed as $0 in the notice

Unit fits — one characterization, each unit's own rules

Physical Sciences & Engineering (demo) 80 strong technical depth: substantial; funds basic research
IPPRA 58 good portfolio topic: mental_behavioral_health; social/behavioral work is substantial; funds basic research; clinical-trial/biomedical core — IPPRA angle is policy/community (capped)
Tom Love Innovation Hub 15 none deep-tech content; no commercialization signal

Description

The goal of this Funding Opportunity Announcement (FOA) is to encourage applications for studies that will enhance knowledge of mechanisms associated with neuropsychiatric symptoms (NPS) in persons with Alzheimer's disease (AD) or Alzheimer's disease-related dementias (ADRD). The findings are expected to advance mechanistic understanding of both biobehavioral and neurobiological pathways leading to NPS. Findings may also provide insight into novel therapeutic targets that can be advanced into interventions to treat and prevent the development of NPS in AD and/or ADRD

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Apply

View on Grants.gov → CONTACT: National Institutes of Health <grantsinfo@nih.gov>

Proposal brief

ONE LLM CALL (~1¢) · CACHED · REQUIRES STAFF KEY

Proposal shell · National Institutes of Health conventions

ONE LLM CALL (~2-3¢) · CACHED · SCAFFOLDING, NOT GHOSTWRITING