IPPRA / Grant Monitor

2026-07-07
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Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R61/R33 Clinical Trial Optional)

PAR-25-158 · National Institutes of Health

biomedical clinical mental behavioral health public health Health

Closes
2026-11-17 · 133 d
Award ceiling
Award floor
Program funding
Expected awards
Cost sharing
No
Posted
2024-11-25
Instrument
Grant
Characterization · gpt-5.4-mini · 2026-07-07

NIH will fund phased R61/R33 projects that develop and test prevention or intervention strategies for fetal alcohol spectrum disorders, with optional clinical trials and priority for applications that include them.

Funds
applied research
University
direct
social behavioral
substantial
life biomedical
central
computational data
minor

⚑ R61/R33 phased mechanism with milestone-based transition to R33 · Clinical trial optional, but highest priority given to applications with clinical trials · Applications may be secondary data analyses or pilot studies in R61 phase · Foreign organizations are eligible under this notice

Unit fits — one characterization, each unit's own rules

IPPRA 58 good peripheral portfolio topic: public_health; signature methods: surveys longitudinal, community engaged; social/behavioral work is substantial; funds applied research; biomedical core — IPPRA health lane is communication/crisis/policy (capped); clinical-trial/biomedical core — IPPRA angle is policy/community (capped)
Physical Sciences & Engineering (demo) 55 good technical depth: minor; funds applied research
Tom Love Innovation Hub 30 weak funds applied research; deep-tech content

Description

This Notice of Funding Opportunity (NOFO) focuses on prevention and intervention strategies for fetal alcohol spectrum disorders (FASD) throughout the lifespan. The intent of this NOFO is to support research that advances (1) prevention approaches to reduce prenatal alcohol exposure and the incidence of FASD and that (2) interventions for FASD. These objectives will be accomplished with the Exploratory/Developmental Phased Award (R61/R33) mechanism, clinical trial optional. The R61 phase will support pilot studies or secondary data analysis for hypothesis development and feasibility, and research testing the hypotheses can be expanded in the R33 phase. The transition to the R33 phase will be determined by NIAAA program staff after evaluation of the achievement of specific milestones set for the R61 phase. Highest priority will be given to applications with clinical trials. Applicants interested in planning clinical trials or adding to current projects may also consider NOFO (TEMP-23832, the R34 option).

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Apply

View on Grants.gov → CONTACT: National Institutes of Health <grantsinfo@nih.gov>

Proposal brief SEE AN EXAMPLE →

A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.

ONE LLM CALL (~1¢) · CACHED · REQUIRES STAFF KEY

Proposal shell · National Institutes of Health conventions SEE AN NIH EXAMPLE →

Funder-faithful document skeletons — National Institutes of Health's document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.

ONE LLM CALL (~2-3¢) · CACHED · SCAFFOLDING, NOT GHOSTWRITING