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2026-07-07
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New Approaches for Measuring Brain Changes Across Longer Timespans (R01 Clinical Trial Optional)

PAR-25-279 · National Institutes of Health

biomedical clinical ai data science education workforce public health Education Health Income Security and Social Services

Closes
2027-05-07 · 304 d
Award ceiling
Award floor
Program funding
Expected awards
Cost sharing
No
Posted
2024-11-25
Instrument
Grant
Characterization · gpt-5.4-mini · 2026-07-07

NIH R01 funding supports multidisciplinary research that develops new or novel methods to measure brain activity, connectivity, genomics, or related neurodevelopmental changes across long timespans in humans or animals.

Funds
applied research
University
direct
social behavioral
minor
physical sciences
minor
engineering
substantial
life biomedical
central
computational data
substantial

⚑ R01; clinical trial optional · Uses NIH parent-style broad eligibility including foreign organizations and many minority-serving/tribal institution categories · Award ceiling listed as $0 in the notice

Unit fits — one characterization, each unit's own rules

Physical Sciences & Engineering (demo) 80 strong technical depth: substantial; funds applied research
IPPRA 58 good peripheral portfolio topic: public_health; social/behavioral work is minor; funds applied research; biomedical core — IPPRA health lane is communication/crisis/policy (capped)
Tom Love Innovation Hub 30 weak funds applied research; deep-tech content

Description

The purpose of this funding opportunity is to encourage multidisciplinary investigators to develop new approaches or apply existing approaches in novel ways to measure brain activity, connectivity, genomics, or other aspects across the age spectrum of neurodevelopment. The overarching goal is to extend our understanding of brain development and aging, including studies of the neurodevelopmental origins of later health and disease. Research can include healthy human participants of any age, specific clinical groups such as those with cognitive, motor, or affective regulation challenges, and/or animal research on these domains of function. The studies can focus on longitudinal neuroanatomical or functional changes at any level, including genetics/genomics, single cells, connectomics, neural population activity patterns, and others. This funding opportunity is intended to encourage technological and conceptual innovation to improve repeated measures across longer epochs of the lifespan, to better predict outcomes at later ages.

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Apply

View on Grants.gov → CONTACT: National Institutes of Health <grantsinfo@nih.gov>

Proposal brief SEE AN EXAMPLE →

A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.

ONE LLM CALL (~1¢) · CACHED · REQUIRES STAFF KEY

Proposal shell · National Institutes of Health conventions SEE AN NIH EXAMPLE →

Funder-faithful document skeletons — National Institutes of Health's document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.

ONE LLM CALL (~2-3¢) · CACHED · SCAFFOLDING, NOT GHOSTWRITING