Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)

PAR-25-322 · National Institutes of Health

biomedical clinical public health social services education workforce Education Environment Food and Nutrition Health Income Security and Social Services

Closes: 2028-08-25 · 780 d
Award ceiling: —
Award floor: —
Program funding: —
Expected awards: —
Cost sharing: No
Posted: 2025-08-25
Instrument: Grant

Characterization · gpt-5.4-mini · 2026-07-07

NIH funds innovative early-stage-investigator research projects with no preliminary data and no clinical trials, for eligible U.S. organizations and certain specified institution types.

Funds: basic research
University: direct
social behavioral: substantial
physical sciences: minor
engineering: minor
life biomedical: central
computational data: minor

⚑ Early Stage Investigator only · No preliminary data allowed · Clinical trials not allowed · Foreign organizations/components not allowed

Unit fits — one characterization, each unit's own rules

IPPRA	84 strong	portfolio topic: public_health; social/behavioral work is substantial; funds basic research
Physical Sciences & Engineering (demo)	55 good	technical depth: minor; funds basic research
Tom Love Innovation Hub	15 none	deep-tech content; no commercialization signal

Description

The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in research direction for an early stage investigator (ESI) and for which no preliminary data exist. Applications submitted to this Notice of Funding Opportunity (NOFO) must not include preliminary data. Applications must include a separate attachment describing the change in research direction.

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Apply

View on Grants.gov → CONTACT: National Institutes of Health <grantsinfo@nih.gov>

IPPRA / Grant Monitor