GREGoRi Technology Integration Center (U01, Clinical Trials Optional)
NIH will fund a cooperative agreement to establish a Technology Integration Center that develops standards, best practices, and a multidimensional dataset to improve rare disease gene and variant discovery and diagnosis.
⚑ Cooperative Agreement (U01) · Clinical Trials Optional · Foreign organizations and non-domestic components of U.S. organizations are not eligible; foreign components are allowed · Major deliverable includes a multidimensional dataset and standards/best practices for rare disease diagnostics
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 90 strong | technical depth: central; funds data infrastructure |
| IPPRA | 45 partial | peripheral portfolio topic: public_health; social/behavioral work is none; funds data/survey infrastructure; biomedical core — IPPRA health lane is communication/crisis/policy (capped); capped at 45 (limited social-science role) |
| Tom Love Innovation Hub | 15 none | deep-tech content; no commercialization signal |
Description
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Technology Integration Center, which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center will be a multidimensional dataset that can be used for the development and benchmarking of novel tools and strategies that facilitate rare disease diagnosis.
Eligibility
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Apply
View on Grants.gov → CONTACT: National Institutes of Health <nhgri-gregor@mail.nih.gov>
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