NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)
This SBIR parent grant funds U.S. small business concerns to conduct feasibility studies and later-stage R&D to develop commercial products, with optional clinical trials.
RESTRICTED TO: SMALL BUSINESS SBIR STTR
⚑ U.S. small business concerns only; universities cannot apply as lead · foreign organizations and non-U.S. components are ineligible · clinical trial optional
Unit fits — one characterization, each unit's own rules
| Tom Love Innovation Hub | 100 strong | SBIR/STTR — core Hub pipeline (faculty founders + small-business partners); funds commercialization; prototyping/demonstration stage; deep-tech content |
| Physical Sciences & Engineering (demo) | 45 partial | technical depth: central; funds commercialization (capped) |
| IPPRA | 25 weak | peripheral portfolio topic: public_health; social/behavioral work is minor; funds commercialization — not a research fit; university can only partner, not lead; biomedical core — IPPRA health lane is communication/crisis/policy (capped); clinical-trial/biomedical core — IPPRA angle is policy/community (capped) |
Description
The Small Business Innovation Research (SBIR) program helps United States small business concerns (SBCs) bring scientific innovations to the marketplace. The SBIR program supports feasibility studies to later research and development (R&D) needed to develop a commercial product.
Eligibility
Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity.Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Unfunded international collaborations or unfunded foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
Apply
View on Grants.gov → CONTACT: National Institutes of Health <SEEDinfo@nih.gov>
Proposal brief SEE AN EXAMPLE →
A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.
Proposal shell · National Institutes of Health conventions SEE AN NIH EXAMPLE →
Funder-faithful document skeletons — National Institutes of Health's document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.