IPPRA / Grant Monitor

2026-07-07
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Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)

RFA-HL-27-004 · National Institutes of Health

biomedical clinical public health Health

Closes
2028-11-07 · 854 d
Award ceiling
$85,000
Award floor
Program funding
$3,900,000
Expected awards
29
Cost sharing
No
Posted
2026-05-12
Instrument
Grant
Characterization · gpt-5.4-mini · 2026-07-07

Small R03 research projects are funded for current or recently completed NHLBI K01, K08, K23, or K25 awardees to extend or branch from their K-award research and generate preliminary data for a future R01-equivalent application.

Funds
basic research
University
ineligible
social behavioral
minor
physical sciences
minor
engineering
minor
life biomedical
central
computational data
minor

RESTRICTED TO: SINGLE NAMED INSTITUTION

⚑ Limited competition: only current or recently completed NHLBI K01/K08/K23/K25 awardees may apply · R03 small grant; project must be completable within 2 years and is intended to produce preliminary data · Minimum 40% protected research effort required during the award period · Foreign organizations, non-domestic components, and foreign components are not allowed

Unit fits — one characterization, each unit's own rules

IPPRA 5 none limited competition — a named institution holds this
Tom Love Innovation Hub 5 none not openly competed
Physical Sciences & Engineering (demo) 5 none limited competition — a named institution holds this

Description

This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that invites applications from eligible organizations to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered. The purpose of this NOFO is to solicit current or recently completed NHLBI K01, K08, K23, and K25 awardees for small grant support to expand their current research objectives or to branch out to a new study emerging from their K award research. This NOFO is intended to facilitate the transition to research independence for these NHLBI K awardees. Current NHLBI K01, K08, K23, and K25 awardees may apply for this R03 support starting in the third year of their K award Project Period. Recently completed NHLBI K01, K08, K23, and K25 award recipients are eligible to apply or resubmit A1 applications if the earliest potential R03 award start date is within two years of the end of their K award Project Period.The R03 grant mechanism supports research projects that can be completed within two years and with limited resources. These projects are expected to generate preliminary data to bolster a subsequent R01-equivalent application. Eligible projects include, but are not limited to, pilot or feasibility studies; proof of concept studies; secondary analysis of existing data; small, self-contained research projects; development of new research methodologies or technologies, or creation of novel experimental model systems.Applicants are required to maintain a minimum of 40% protected research effort during the R03 award period. This requirement can be fulfilled through a combination of effort on the proposed R03 project and other research projects, irrespective of funding source.For current and former K23 awardees, the research proposed in the R03 application may or may not include patient-oriented research.

Eligibility

Only the following NHLBI K01, K08, K23, and K25 awardees are eligible to apply for this funding opportunity.Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Apply

View on Grants.gov → CONTACT: National Institutes of Health <NHLBI_R03@nih.gov>

Proposal brief SEE AN EXAMPLE →

A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.

ONE LLM CALL (~1¢) · CACHED · REQUIRES STAFF KEY

Proposal shell · National Institutes of Health conventions SEE AN NIH EXAMPLE →

Funder-faithful document skeletons — National Institutes of Health's document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.

ONE LLM CALL (~2-3¢) · CACHED · SCAFFOLDING, NOT GHOSTWRITING