NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)
This program funds U.S. small businesses collaborating with nonprofit research institutions to do feasibility and later-stage R&D for commercializable scientific innovations, with optional clinical trials.
RESTRICTED TO: SMALL BUSINESS SBIR STTR
⚑ University may participate only as a nonprofit research institution partner; it cannot be the lead applicant. · Foreign organizations and non-domestic components are not eligible. · Clinical trials are optional, not required.
Unit fits — one characterization, each unit's own rules
| Tom Love Innovation Hub | 100 strong | SBIR/STTR — core Hub pipeline (faculty founders + small-business partners); funds commercialization; prototyping/demonstration stage; deep-tech content |
| Physical Sciences & Engineering (demo) | 35 weak | technical depth: substantial; funds commercialization (capped) |
| IPPRA | 25 weak | peripheral portfolio topic: public_health; social/behavioral work is minor; funds commercialization — not a research fit; university can only partner, not lead; clinical-trial/biomedical core — IPPRA angle is policy/community (capped) |
Description
The Small Business Technology Transfer (STTR) grant program helps United States small business concerns (SBCs) that partner with a nonprofit research institution bring scientific innovations to the marketplace. The STTR program supports feasibility studies to later stage research and development (R&D) needed to develop a commercial product.
Eligibility
Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity.Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Unfunded international collaborations or unfunded foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
Apply
View on Grants.gov → CONTACT: National Institutes of Health <SEEDinfo@nih.gov>
Proposal brief SEE AN EXAMPLE →
A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.
Proposal shell · National Institutes of Health conventions SEE AN NIH EXAMPLE →
Funder-faithful document skeletons — National Institutes of Health's document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.