IPPRA / Grant Monitor

2026-07-07
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Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)

RFA-CA-27-021 · National Institutes of Health

biomedical clinical ai data science computing communications public health Health

Closes
2026-10-19 · 104 d
Award ceiling
$600,000
Award floor
$50,000
Program funding
$1,800,000
Expected awards
2
Cost sharing
No
Posted
2026-05-21
Instrument
Cooperative Agreement
Characterization · gpt-5.4-mini · 2026-07-07

NIH/NCI funds sustainment and ongoing enhancement of existing, widely used informatics tools and resources that support cancer research, with documentation, outreach, and user-engagement activities for the research community.

Funds
data infrastructure
University
direct
social behavioral
minor
physical sciences
minor
engineering
substantial
life biomedical
substantial
computational data
central

⚑ Cooperative Agreement (U24) · Clinical Trial Optional · Award ceiling $600,000 · Focus is sustainment of existing resources, not early-stage development

Unit fits — one characterization, each unit's own rules

Physical Sciences & Engineering (demo) 90 strong technical depth: central; funds data infrastructure
IPPRA 58 good peripheral portfolio topic: public_health; signature methods: community engaged; social/behavioral work is minor; funds data/survey infrastructure
Tom Love Innovation Hub 15 none deep-tech content; no commercialization signal

Description

This Notice of Funding Opportunity (NOFO) solicits applications for the continued development and sustainment of high value informatics research resources to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO is focused on sustaining operations and maintaining and evolving the scientific relevance of existing, widely-adopted informatics tools and resources. This is in contrast to early-stage and advanced development efforts to generate these tools and resources that will be supported by companion ITCR NOFOs. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, the application must provide clear justification for why the research resource should be maintained and how it has benefited and will continue to benefit the cancer research field. In addition, mechanisms for assessing and maximizing the value of the resource to researchers and supporting close engagement between the resource and the targeted research community should be described.This NOFO invites applications to support the sustained operations of informatics technology resources that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis is on sustaining resources that have had a demonstrated impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:Evidence that the technology has had significant impact on cancer research to date and the sustainment plan will lead to the continued advancement of cancer researchRobust plans for supporting the end-user community including documentation, training, and other outreach activitiesClear processes for engaging end users to address emerging needs of the targeted research communities to ensure that the research resource maintains relevance to the research it supports

Eligibility

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Apply

View on Grants.gov → CONTACT: National Institutes of Health <nciitcr@mail.nih.gov>

Proposal brief SEE AN EXAMPLE →

A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.

ONE LLM CALL (~1¢) · CACHED · REQUIRES STAFF KEY

Proposal shell · National Institutes of Health conventions SEE AN NIH EXAMPLE →

Funder-faithful document skeletons — National Institutes of Health's document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.

ONE LLM CALL (~2-3¢) · CACHED · SCAFFOLDING, NOT GHOSTWRITING