IPPRA / Grant Monitor

2026-07-07
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Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)

RFA-CA-27-019 · National Institutes of Health

biomedical clinical ai data science computing communications public health Health

Closes
2027-10-19 · 469 d
Award ceiling
$300,000
Award floor
$50,000
Program funding
$2,400,000
Expected awards
5
Cost sharing
No
Posted
2026-05-21
Instrument
Cooperative Agreement
Characterization · gpt-5.4-mini · 2026-07-07

Funds early-stage development of novel informatics tools and resources for cancer research and management, from prototyping through initial dissemination, for eligible applicants including U.S. universities.

Funds
applied research
University
direct
social behavioral
minor
physical sciences
minor
engineering
substantial
life biomedical
central
computational data
central

⚑ U01 cooperative agreement · clinical trial optional · award ceiling $300,000 · foreign organizations and foreign components eligible

Unit fits — one characterization, each unit's own rules

Physical Sciences & Engineering (demo) 90 strong technical depth: central; funds applied research
IPPRA 58 good peripheral portfolio topic: public_health; social/behavioral work is minor; funds applied research; biomedical core — IPPRA health lane is communication/crisis/policy (capped)
Tom Love Innovation Hub 45 partial funds applied research; prototyping/demonstration stage; deep-tech content

Description

This Notice of Funding Opportunity (NOFO) solicits applications for the development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO is focused on early-stage development from prototyping to initial dissemination. Early-stage development is defined for the purpose of this NOFO as initial tool development or the significant modification of existing tools for new applications. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, proposed development plans must have a clear rationale for why the proposed technology is needed and how it will benefit the cancer research field. In addition, mechanisms to solicit feedback from driving research projects and other users throughout the development process must be included.This NOFO encourages applications that involve the development of new, user-friendly informatics technologies that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis is on uniqueness and potential impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:Potential to advance driving cancer research projects and the cancer research field in generalNovel informatics capabilities for the targeted cancer research domainCompelling plans and processes for engaging end users to evaluate and apply the tool or resourceA realistic timeline and milestones for technology development

Eligibility

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Apply

View on Grants.gov → CONTACT: National Institutes of Health <nciitcr@mail.nih.gov>

Proposal brief SEE AN EXAMPLE →

A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.

ONE LLM CALL (~1¢) · CACHED · REQUIRES STAFF KEY

Proposal shell · National Institutes of Health conventions SEE AN NIH EXAMPLE →

Funder-faithful document skeletons — National Institutes of Health's document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.

ONE LLM CALL (~2-3¢) · CACHED · SCAFFOLDING, NOT GHOSTWRITING