Kidney Precision Medicine Project Tissue Interrogation Sites (U01 Clinical Trial Not Allowed)
NIH will fund cooperative agreement Tissue Interrogation Sites to perform integrated multi-modal analysis of human kidney biopsy tissue for the Kidney Precision Medicine Project to identify disease pathways and subgroups supporting precision clinical trials.
⚑ Clinical Trial Not Allowed · Foreign Organizations and foreign components are not allowed · Cooperative Agreement with active NIH/project-wide participation expectations
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 90 strong | technical depth: central; funds applied research |
| IPPRA | 58 good | portfolio topic: public_health; social/behavioral work is minor; funds applied research |
| Tom Love Innovation Hub | 30 weak | funds applied research; deep-tech content |
Description
This Notice of Funding Opportunity (NOFO) requests applications for Kidney Precision Medicine Project (KPMP) Tissue Interrogation Sites (TIS) to use highly integrated multi-modal analytic pipelines to interrogate human kidney biopsy tissue to discover and define new disease pathways and subgroups that enable precision clinical trials. All KPMP personnel will actively participate in scientific discovery and promote open science.
Eligibility
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Apply
View on Grants.gov → CONTACT: National Institutes of Health <NIDDK_KUH@nih.gov>
Proposal brief
Proposal shell · National Institutes of Health conventions
Legacy IPPRA LLM assessment (v2.0, for comparison)
0/100 · gpt-5.4-mini · 2026-07-06
This is a biomedical, tissue-interrogation cooperative agreement focused on kidney disease biology and precision medicine, with no meaningful public policy, behavioral, community, or communication research component for IPPRA’s portfolio. It is open to U.S. domestic applicants, but it is not a fit for a public-policy research institute.
Legacy scoring history
| 2026-07-06 | 0 | gpt-5.4-mini | This is a biomedical, tissue-interrogation cooperative agreement focused on kidney disease biology and precision medicine, with no meaningful public policy, behavioral, community, or communication research component for IPPRA’s portfolio. It is open to U.S. domestic applicants, but it is not a fit for a public-policy research institute. |
| 2026-07-06 | 12 | gpt-5.4-mini | This is a biomedical precision-medicine opportunity focused on kidney tissue analytics and disease pathways, with no meaningful behavioral, policy, community, or communication component that IPPRA would typically anchor. A public university is eligible, but the topic is far outside IPPRA’s core social-science and risk-communication portfolio, so relevance is very limited. |