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2026-07-07
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Maximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI)

PAR-27-032 · National Institutes of Health

biomedical clinical public health ai data science Health

Closes
2029-02-06 · 945 d
Award ceiling
Award floor
Program funding
Expected awards
Cost sharing
No
Posted
2026-05-12
Instrument
Grant
Characterization · gpt-5.4-mini · 2026-07-07

Provides NIH NIGMS research funding for early-stage investigators to support an independent program of biomedical/basic research and associated trainee mentoring.

Funds
basic research
University
direct
physical sciences
minor
engineering
minor
life biomedical
central
computational data
minor

⚑ Early Stage Investigator-only MIRA mechanism; eligibility must be checked against the NOFO. · Foreign components are allowed, but non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible to apply.

Unit fits — one characterization, each unit's own rules

Physical Sciences & Engineering (demo) 65 good technical depth: minor; funds basic research
IPPRA 45 partial peripheral portfolio topic: public_health; social/behavioral work is none; funds basic research; biomedical core — IPPRA health lane is communication/crisis/policy (capped); capped at 45 (limited social-science role)
Tom Love Innovation Hub 15 none deep-tech content; no commercialization signal

Description

The Maximizing Investigators' Research Award (MIRA) for Early Stage Investigators (ESIs) provides support for ESIs with a program of research that aligns with the NIGMS mission.MIRA distributes funding among promising investigators across the country. The goal is to boost scientific productivity and the chances for important breakthroughs.Through this program, investigators can:Receive independent research funding early to start and sustain strong research careers.Explore new, unique research areas in the NIGMS mission.Take on ambitious, creative projects.Shift focus to include emerging techniques and technologies as needed.Devote more time to mentoring trainees in a stable research environment.

Eligibility

Refer to the Eligibility section in the NOFO for additional information on eligibility.Foreign institutions: Foreign components, as defined in the NIH Grants Policy Statement, are allowed.These types of organizations are not eligible to apply: Non-domestic (non-U.S.) entities (foreign institutions), Non-domestic (non-U.S.) components of U.S. organizations.

Apply

View on Grants.gov → CONTACT: National Institutes of Health <NIGMS-ESIMIRA@nigms.nih.gov>

Proposal brief SEE AN EXAMPLE →

A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.

ONE LLM CALL (~1¢) · CACHED · REQUIRES STAFF KEY

Proposal shell · National Institutes of Health conventions SEE AN NIH EXAMPLE →

Funder-faithful document skeletons — National Institutes of Health's document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.

ONE LLM CALL (~2-3¢) · CACHED · SCAFFOLDING, NOT GHOSTWRITING