The NIDDK Disorders of Gastrointestinal Interoception Consortium (DGIC) - Clinical Research Centers (U01 Clinical Trial Not Allowed)
Supports cooperative agreement clinical research centers that study gastrointestinal interoception mechanisms, biomarkers, and novel therapeutic targets for future GI symptom and dysmotility research.
⚑ Clinical trial not allowed · Cooperative agreement (U01) · Parallel companion NOFO; applicant should check whether this is the Clinical Research Centers component of the consortium
This is a biomedical/clinical mechanistic consortium on gastrointestinal interoception, dysmotility, biomarkers, and future therapeutics. It is far outside IPPRA’s social-behavioral program lines in risk perception, hazard communication, energy/security, education policy, and public opinion.
JUDGED AGAINST THE ROSTER'S PUBLICATION DOSSIER · GPT-5.4-MINI · 2026-11-04
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 80 strong | technical depth: substantial; funds applied research |
| IPPRA | 58 good | peripheral portfolio topic: public_health; social/behavioral work is minor; funds applied research; biomedical core — IPPRA health lane is communication/crisis/policy (capped); clinical-trial/biomedical core — IPPRA angle is policy/community (capped) |
| Tom Love Innovation Hub | 30 weak | funds applied research; deep-tech content |
Description
This Notice of Funding Opportunity (NOFO) invites new applications to participate in the Diseases of Gastrointestinal Interoception Consortium (DGIC). The overall objectives of this consortium are to: 1) identify the underlying mechanisms that link altered GI interception more directly to GI dysmotility and symptoms; 2) identify disease or response biomarkers that better assess pathophysiology or treatment efficacy; and 3) leverage state-of-the-art technologies to identify novel therapeutic targets that could be assessed in future clinical trials.
This NOFO uses a cooperative agreement mechanism (U01) and runs in parallel with a companion NOFO ( RFA-DK-28-214) .
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Apply
View on Grants.gov → CONTACT: National Institutes of Health <terez.shea-donohue@nih.gov>
Proposal brief SEE AN EXAMPLE →
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Proposal shell · National Institutes of Health conventions SEE AN NIH EXAMPLE →
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