NIH Director’s Transformative Research Award for Individual and Group Science (R01 Clinical Trial Optional)
NIH funds high-risk, high-reward transformative biomedical research by individual scientists or groups, including basic, translational, or clinical projects, with no preliminary data required.
⚑ Foreign organizations and non-domestic components of U.S. organizations are not eligible; foreign components are allowed. · Clinical trials optional. · No preliminary data required. · Award is part of NIH High-Risk, High-Reward Research / Common Fund; applications may be individual or group science.
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 80 strong | technical depth: substantial; funds basic research |
| IPPRA | 58 good | portfolio topic: public_health; social/behavioral work is minor; funds basic research; clinical-trial/biomedical core — IPPRA angle is policy/community (capped) |
| Tom Love Innovation Hub | 30 weak | prototyping/demonstration stage; deep-tech content |
Description
The NIH Director"s Transformative Research Award supports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. Applications in any area within the biomedical sciences are welcome; topics may involve basic, translational, or clinical research. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in a broad area of relevance to the NIH. The NIH Director"s Transformative Research Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.
Eligibility
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Apply
View on Grants.gov → CONTACT: National Institutes of Health <Transformative_Awards@mail.nih.gov>