NextTech: Translational Development of Next-Generation Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)
NIH funds translation and development of next-generation diagnostic and therapeutic devices for disorders within the BRAIN and HEAL missions, up to readiness for first-in-human clinical trials, for eligible applicants including universities.
⚑ Clinical trials not allowed · Supports device translation and human-use readiness, not first-in-human enrollment · Relevant to NIH BRAIN and HEAL initiative missions
This is a biomedical device-development program aimed at translational neuroscience/addiction technologies and readiness for first-in-human trials, which is far outside IPPRA’s social-behavioral/public opinion, policy, and hazard-communication lines. The team might engage only peripherally on public acceptance or implementation questions, but it is not plausibly a PI-level fit for any member.
JUDGED AGAINST THE ROSTER'S PUBLICATION DOSSIER · GPT-5.4-MINI · 2026-10-24
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 80 strong | technical depth: central; funds applied research |
| IPPRA | 58 good | peripheral portfolio topic: public_health; social/behavioral work is minor; funds applied research; biomedical core — IPPRA health lane is communication/crisis/policy (capped) |
| Tom Love Innovation Hub | 45 partial | funds applied research; prototyping/demonstration stage; deep-tech content |
Description
This Notice of Funding Opportunity (NOFO) is to encourage applications from investigators to advance the development and translation of next-generation technologies to prevent, monitor, diagnose, and treat disorders within the missions of the NIH Brain Research through Advancing Innovative Neurotechnologies (BRAIN) and The Helping to End Addiction Long-term (HEAL) Initiatives. Awarded activities will facilitate the translation of new devices up to the stage of readiness for first in human (FIH) clinical trials by overcoming key challenges identified during preliminary proof-of-concept studies. The scope of the program includes technology development and optimization, and studies to prepare for approvals for human use.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Apply
View on Grants.gov → CONTACT: National Institutes of Health <NIBIB_Devices@NIH.gov>
Proposal brief SEE AN EXAMPLE →
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Proposal shell · National Institutes of Health conventions SEE AN NIH EXAMPLE →
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