Immune Tolerance Network (UM1 Clinical Trial Required)
This cooperative agreement funds continuation of the Immune Tolerance Network to design, conduct, and share results from clinical trials and integrated mechanistic studies on tolerogenic therapies for allergic disease, autoimmune disease, and transplant-related immune consequences.
⚑ Clinical trial required · Cooperative agreement with network-style responsibilities · Foreign institutions, tribal governments, federal agencies, territorial entities, faith-based/community-based, and regional organizations are listed as eligible applicants · Award ceiling listed as $0 in the notice
This is a biomedical clinical-trial network for tolerogenic therapies in allergy, autoimmunity, and transplantation, which is far outside IPPRA’s social-science, risk-perception, and policy-evaluation portfolio. The team might engage only tangentially on communication or public-health implications, but not as a plausible PI-led fit.
JUDGED AGAINST THE ROSTER'S PUBLICATION DOSSIER · GPT-5.4-MINI · 2026-10-21
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 70 strong | technical depth: substantial; funds applied research |
| IPPRA | 45 partial | peripheral portfolio topic: public_health; social/behavioral work is none; funds applied research; biomedical core — IPPRA health lane is communication/crisis/policy (capped); clinical-trial/biomedical core — IPPRA angle is policy/community (capped); capped at 45 (limited social-science role) |
| Tom Love Innovation Hub | 30 weak | funds applied research; deep-tech content |
Description
The purpose of this notice of funding opportunity (NOFO) is to support applications to continue the Immune Tolerance Network (ITN). The primary objective of the Network is to develop tolerogenic therapies for immune-mediated disorders. The three main clinical areas of work are: 1) Allergic diseases and asthma; 2) Autoimmune diseases; and 3) Immune-mediated consequences of transplantation. The core functions of the ITN include designing, conducting, and sharing the results of clinical trials and performing integrated mechanistic studies.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Apply
View on Grants.gov → CONTACT: National Institutes of Health <ITN_UM1@mail.nih.gov>
Proposal brief SEE AN EXAMPLE →
A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.
Proposal shell · National Institutes of Health conventions SEE AN NIH EXAMPLE →
Funder-faithful document skeletons — National Institutes of Health's document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.