IPPRA / Grant Monitor

2026-07-07
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​Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities​

DFOP0018449 · Bureau of Arms Control and Nonproliferation

national security defense ai data science biomedical clinical international affairs Science & Technology R&D

Closes
2026-07-21 · 14 d
Award ceiling
$4,000,000
Award floor
Program funding
$4,000,000
Expected awards
3
Cost sharing
No
Posted
2026-06-29
Instrument
Cooperative Agreement, Other
Characterization · gpt-5.4-mini · 2026-07-07

This competition funds U.S.-based projects by domestic nonprofits, educational institutions, for-profits, or federal entities to identify, evaluate, and develop safeguards against proliferation misuse risks from AI-enabled chemical and biological molecular models.

Funds
applied research
University
direct
social behavioral
minor
physical sciences
substantial
engineering
substantial
life biomedical
substantial
computational data
central

⚑ Lead applicant must be based in the U.S. · Domestic nonprofits, educational institutions, for-profits, and U.S. federal government entities may apply. · Cooperative agreement / assistance award; proposal may be a full project or targeted subset of objectives. · Application should indicate whether there is a collaborating partner separately responding to the solicitation.

Unit fits — one characterization, each unit's own rules

Physical Sciences & Engineering (demo) 90 strong technical depth: central; funds applied research
IPPRA 58 good portfolio topic: national_security_defense (primary); social/behavioral work is minor; funds applied research
Tom Love Innovation Hub 45 partial funds applied research; prototyping/demonstration stage; deep-tech content

Description

The Department of State’s Office of the Nonproliferation and Disarmament Fund (ACN/NDF) is pleased to announce an open competition for assistance awards through this Notice of Funding Opportunity (NOFO). ACN/NDF invites domestic non-profit/non-governmental organizations, educational institutions, and for-profit organizations to submit proposals for projects that will advance the mission of NDF’s efforts to identify, evaluate, and develop safeguards to counter the misuse risks enabled by the proliferation of chemical and biological Artificial Intelligence (AI) models (CBAIMs). Proposals may not exceed the total availability of funds under this NOFO. ACN/NDF welcomes proposals that fully address all or a clearly articulated, targeted subset of the key objectives of this NDF line of effort (Section II). Please indicate whether the proposal involves collaboration with a partner organization that is separately responding to this solicitation.

Eligibility

U.S. Federal Government Entities. Lead applicant organizations must be based in the U.S. to be eligible.

Apply

View on Grants.gov → CONTACT: Bureau of Arms Control and Nonproliferation <acn-ndf-grants@state.gov>

Proposal brief

ONE LLM CALL (~1¢) · CACHED · REQUIRES STAFF KEY

Proposal shell · Federal (generic) conventions

ONE LLM CALL (~2-3¢) · CACHED · SCAFFOLDING, NOT GHOSTWRITING