Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS)
ARPA-H will fund multiple Other Transaction awards for work on its SURPASS program to develop a simulation-augmented, real-time platform adaptive seamless trial capability.
⚑ ARPA-H solicitation using Other Transaction Agreements, not a standard grant · Applicant restrictions apply under the federal contract notice; exact eligible applicant classes must be checked in the solicitation attachments · Multiple awards anticipated · Informational webinar and Proposers’ Day listed in notice
This is a biomedical clinical-trial methods opportunity centered on adaptive trial platforms, simulation, and health intervention development, which is far outside IPPRA’s core social-science lines. The team could be adjacent methodologically at best, but none of the named researchers’ published programs are a plausible PI fit here.
JUDGED AGAINST THE ROSTER'S PUBLICATION DOSSIER · GPT-5.4-MINI · 2026-10-01
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 90 strong | technical depth: central; funds applied research |
| IPPRA | 58 good | peripheral portfolio topic: public_health; social/behavioral work is minor; funds applied research; biomedical core — IPPRA health lane is communication/crisis/policy (capped); clinical-trial/biomedical core — IPPRA angle is policy/community (capped) |
| Tom Love Innovation Hub | 30 weak | funds applied research; deep-tech content |
Description
The Advanced Research Projects Agency for Health (ARPA-H) posts this solicitation in support of its Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS) Program. ARPA-H anticipates multiple Other Transaction Agreement awards will result from this opportunity. Interested parties are invited to review the attached Solicitation (ARPA-H-SOL-26-164) and associated attachments. As detailed in Special Notice ARPA-H-SN-26-164, ARPA-H will host an informational webinar on 15 OCT 2026 and a 2-day Proposers’ Day on 6 and 9 NOV 2026 in support of SURPASS. All questions related to SURPASS should be submitted to SURPASS@ARPA-H.GOV.
Eligibility
Applicant restrictions (federal contract). Set-aside: . Notice type: Solicitation. Organization: HEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH / ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H).
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