Proactive Health Office (PHO) Mission Office Innovative Solutions Opening (ISO)
ARPA-H is soliciting proposals for proactive health solutions that improve prevention, early detection, prophylaxis, and system-level delivery before disease or major quality-of-life decline, for eligible applicants under the solicitation.
⚑ Federal contract solicitation through ARPA-H; applicants must use the ARPA-H Solutions Site submission portal. · Amendment 4 is effective immediately; proposals after a prior Solution Summary must comply with the amended administrative and policy requirements. · No award ceiling stated. · Two-step process indicated: Solution Summary and then proposal.
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 80 strong | technical depth: substantial; funds applied research |
| IPPRA | 58 good | peripheral portfolio topic: public_health; signature methods: community engaged; social/behavioral work is substantial; funds applied research; biomedical core — IPPRA health lane is communication/crisis/policy (capped); clinical-trial/biomedical core — IPPRA angle is policy/community (capped) |
| Tom Love Innovation Hub | 45 partial | funds applied research; prototyping/demonstration stage; deep-tech content |
Description
The Proactive Health Office (PHO) at ARPA-H is seeking solutions to improve the healthspan and health outcomes of Americans prior to the onset of disease and/or the development of diminished quality of life from illness. Specifically, PHO hypothesizes that 1) population-level improvements in access to and uptake of disease prevention and wellness-promoting behaviors and 2) development of novel early-detection methods and prophylactic interventions could drastically improve the health of American throughout their lives, and 3) that system level innovations are required for delivery of proactive health effectively. Solution summary submissions must be submitted to: https://solutions.arpa-h.gov Questions must be submitted to: https://solutions.arpa-h.gov/Ask-A-Question/ Proposal submission should be submitted to: https://solutions.arpa-h.gov/Submit-Proposal/ Amendment 4 is effective immediately; however, if an entity has previously submitted a Solution Summary and a proposal, no action is required related to changes described in the amendment. If only a Solution Summary has been submitted; any future proposal must comply with this amendment. Amendment 04 includes the following changes: Updated Administrative and National Policy Requirements document (Note other Bundle of Attachment documents are unchanged) Minor changes throughout the ISO, including, but not limited to: Updating the name from ARPA-H Solution Submission Portal to ARPA-H Solutions Site, notation in paragraph 2.3, and revised language in Section 6.1 Research Security Disclosures to align with the updated Bundle of Attachments document.
Eligibility
Applicant restrictions (federal contract). Set-aside: . Notice type: Solicitation. Organization: HEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH / ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H).
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Proposal brief SEE AN EXAMPLE →
A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.
Proposal shell · HHS services agencies (SAMHSA / HRSA / CDC / ACF) conventions SEE AN HHS EXAMPLE →
Funder-faithful document skeletons — HHS services agencies (SAMHSA / HRSA / CDC / ACF)'s document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.