Technology InteGrator and AcceleratoR (TIGAR)
ARPA-H will fund solutions that enable temperature-flexible storage and distribution of regenerative tissues and organs, including enabling technologies for thick tissues and complex biological systems.
⚑ ARPA-H solicitation with federal contract language; not a grant program in the usual sense · Proposer's Day referenced in special notice · Solution video and supplemental slide requirements · No set-aside stated
This is an ARPA-H biomedical/regenerative tissue storage and materials/biotech technology topic, which is far outside IPPRA’s usual social-science portfolio on climate, hazards, energy, and public risk perception. No roster member has a plausible PI-level publication line in regenerative medicine, biomedical preservation, or tissue engineering.
JUDGED AGAINST THE ROSTER'S PUBLICATION DOSSIER · GPT-5.4-MINI · 2026-07-07
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 90 strong | technical depth: central; funds applied research |
| Tom Love Innovation Hub | 45 partial | funds applied research; prototyping/demonstration stage; deep-tech content |
| IPPRA | 40 partial | outside portfolio topics; social/behavioral work is none; funds applied research; biomedical core — IPPRA health lane is communication/crisis/policy (capped) |
Description
Amendment 3 (1) Appendix B was updated to remove track changes (2) Appendix C4 was updated to remove an erroneous comment. Amendment 2 (1) Instructions on how to submit a Solution Video were added to the ISO (see pages 7-8). (2) Information related to the Video Captions file was added to Appendix B.0 (Solution Video Format and Instructions). (3) The instructions in Appendix B.1 (Template for Supplemental Slides) were simplified, and a Cost Summary slide was added (see Slide 7). (4) Appendix C.3 was updated to reference "Phase" rather than "Year" for clarity. (5) The Administation and National Policy document in Appendix C.4 was replaced with an updated document. Amendment 1 The ISO was updated with the new webinar and webinar registration dates. Effort Description: TIGAR Exploratory Topic will forge entirely new paths to stabilizing regenerative tissues and organs by seeding the development of enabling technologies that can unlock temperature-flexible storage in increasingly larger and more complex biological systems. Solutions may involve any combination of new materials, artificial intelligence/machine learning, high-throughput screening methods, biological interventions, devices, processing methods, analytical technology, and packaging approaches that can overcome current roadblocks and yield a leap in the ability to store and distribute complex biologics, without introducing high cost or complexity. Strategies that reduce reliance on strictly controlled temperature zones and can ensure safe storage in a range of environmental conditions are preferred. While long-term temperature-flexible storage is ideal, any advance that removes logistical hurdles or establishes shelf-life stability at easy to maintain temperatures (preferably non-cryogenic) will be considered. Innovations at the cellular level without a strategy for deployment in thick tissues will not be considered. Please ensure to follow this opportunity for any updates. For more information on the TIGAR Exploratory Topic visit: https://arpa-h.gov/explore-funding/initiatives-and-sprints/tigar For information on Proposer's Day details and registration information, please see Special Notice ARPA-H-SN-26-142
Eligibility
Applicant restrictions (federal contract). Set-aside: No Set aside used. Notice type: Solicitation. Organization: HEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH / ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H).
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