Area of Interest under PHO ISO: ASCENT-IBO
ARPA-H will fund work under the ASCENT-IBO special notice to accelerate the safe clinical evaluation of ibogaine for opioid use disorder outcomes.
⚑ Special Notice / federal contract mechanism; read attached notice for exact applicant eligibility and submission rules. · Proposers' Day mentioned. · Opportunity is tied to a specific AOI under ASCENT-IBO and builds on ARPA-H-SN-26-156.
This is a biomedical/clinical addiction-treatment opportunity focused on ibogaine and opioid use disorder, which is outside IPPRA’s usual social-behavioral lines. The team might have limited relevance on public attitudes toward emerging treatments, but not as PI-level program work.
JUDGED AGAINST THE ROSTER'S PUBLICATION DOSSIER · GPT-5.4-MINI · 2026-08-13
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 65 good | technical depth: substantial; funds applied research |
| IPPRA | 53 partial | peripheral portfolio topic: public_health; social/behavioral work is minor; funds applied research; eligibility unclear — verify in the NOFO; biomedical core — IPPRA health lane is communication/crisis/policy (capped); clinical-trial/biomedical core — IPPRA angle is policy/community (capped) |
| Tom Love Innovation Hub | 30 weak | funds applied research; deep-tech content |
Description
See attached Special Notice ARPA-H-SN-26-158: Accelerating Safe Clinical Evaluation of Novel Treatments: Ibogaine for Better outcomes in OUD (ASCENT-IBO) This Special Notice builds upon ARPA-H-SN-26-156 and includes details related to a Proposers’ Day event.
Eligibility
Applicant restrictions (federal contract). Set-aside: . Notice type: Special Notice. Organization: HEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH / ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H).
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