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2026-07-07
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BARDA DRIVe EZ-BAA (EZBAA - 22-100-SOL-00003)

DRIVeEZBAA22100SOL00003 · OFFICE OF ASSISTANT SECRETARY FOR PREPAREDNESS AND RESPONSE · BARDA - ASPR / DAAPPO / BARDA DCMA

biomedical clinical public health ai data science computing communications

Closes
2027-10-18 · 468 d
Award ceiling
Award floor
Program funding
Expected awards
Cost sharing
No
Posted
2023-09-13
Instrument
Characterization · gpt-5.4-mini · 2026-07-07

BARDA’s EZ-BAA funds proposals for biomedical countermeasure and preparedness development in specified areas of interest, including vaccines, diagnostics, therapeutics, and digital/at-home medical countermeasures.

Funds
applied research
University
direct
social behavioral
minor
physical sciences
minor
engineering
substantial
life biomedical
central
computational data
substantial

⚑ Federal contract solicitation (not a grant); eligibility and submission rules are governed by the EZ-BAA and area-of-interest-specific notices/amendments. · Multiple AOIs open/close on different schedules; applicants must check the specific AOI and current amendment before submitting. · Award ceiling not stated in the summary provided.

Unit fits — one characterization, each unit's own rules

Physical Sciences & Engineering (demo) 80 strong technical depth: substantial; funds applied research
IPPRA 58 good peripheral portfolio topic: public_health; social/behavioral work is minor; funds applied research; biomedical core — IPPRA health lane is communication/crisis/policy (capped); clinical-trial/biomedical core — IPPRA angle is policy/community (capped)
Tom Love Innovation Hub 45 partial funds applied research; prototyping/demonstration stage; deep-tech content

Description

This announcement serves as a reissuance of the BARDA DRIVe EZ-BAA, now known as EZ-BAA-22-100-SOL-00003. This announcement hereby supersedes and replaces prior iterations of the BARDA DRIVe EZ-BAA (e.g. BAA-20-100-SOL-0002). Please reference the attached announcement and applicable amendments for specifics. Additionally, please visit https://drive.hhs.gov/. _______ Amendment 001: This amendment to the EZBAA hereby opens the following research areas of interest ("AOI"). Please review the amendment for details of each AOI, including closing dates: AOI #15: ReDIRECT AOI #16: Lab at Home AOI #17: Digital MCMs AOI #18: Host-Directed Therapeutics AOI #19: Healing Lungs AOI #20: DRIVe Forward AOI #21: Vaccines on Demand AOI #22: ReBooT AOI #23: Host-Based Diagnostics _____ 11/8/22 - Please see Amendment 002 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Adding the the following Area of Interest (AOI): AOI #24: REPAIR 2. Clarifying an adminstrative error. _____ 11/14/22 - Please see Amendment 003 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Revising the following Area of Interest (AOI): AOI #19: Healing Lungs _____ 12/15/22 - Please see Amendment 004 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): AOI #21: Vaccines on Demand ______ 1/11/23 - Please see Amendment 005 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Pausing the following Area of Interest (AOI) by establishing a new closing date of February 15, 2023 at 12:00PM ET: AOI #15: ReDIRECT ______ 2/1/23 - Please see Amendment 006 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): AOI #19: Healing Lungs 2. Updating the closing date for the following Area of Interest (AOI): AOI #17: Digital MCMs 3. Updating the closing date for the following Area of Interest (AOI): AOI #16: Lab at Home 4. Revising the following Area of Interest (AOI): AOI #16: Lab at Home ______ 2/3/23 - Please see Amendment 007 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): AOI #24: REPAIR ______ 5/1/23 - Please see Amendment 008 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Adding the following Area of Interest (AOI): AOI #25: FASTx 2. Updating the language in Section III (F) of the Easy Broad Agency Announcement titled “Plus (+) Phase”. ______ 5/18/23 - Please see Amendment 009 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Reopening the following Area of Interest (AOI), which is reopened to support project Next Gen: AOI #21: Vaccines on Demand ______ 5/25/23 - Please see Amendment 010 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Revising the following Area of Interest (AOI): AOI #24: REPAIR 2. Updating the closing date for the following Area of Interest (AOI): AOI #24: REPAIR ______ 6/27/23 - Please see Amendment 011 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Closing the following Area of Interest (AOI): AOI #18: Host-Directed Therapeutics 2. Closing the following Area of Interest (AOI): AOI #23: Host-Based Diagnostics 3. Updating the closing date for the following Area of Interest (AOI): AOI #19: Healing Lungs ______ 9/13/23 - Please see Amendment 012 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): AOI #16: Lab at Home 2. Updating the closing date for the following Area of Interest (AOI): AOI #17: Digital MCMs 3. Updating the closing date for the following Area of Interest (AOI): AOI #19: Healing Lungs 4. Revising the following Area of Interest (AOI): AOI #16 Lab at Home 5. Adding the following Area of Interest (AOI): AOI #26: Agnostic Diagnostic _______

Eligibility

Applicant restrictions (federal contract). Set-aside: . Notice type: Solicitation. Organization: HEALTH AND HUMAN SERVICES, DEPARTMENT OF / OFFICE OF ASSISTANT SECRETARY FOR PREPAREDNESS AND RESPONSE / BARDA - ASPR / DAAPPO / BARDA DCMA.

Apply

View on Grants.gov →

Proposal brief SEE AN EXAMPLE →

A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.

ONE LLM CALL (~1¢) · CACHED · REQUIRES STAFF KEY

Proposal shell · HHS services agencies (SAMHSA / HRSA / CDC / ACF) conventions SEE AN HHS EXAMPLE →

Funder-faithful document skeletons — HHS services agencies (SAMHSA / HRSA / CDC / ACF)'s document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.

ONE LLM CALL (~2-3¢) · CACHED · SCAFFOLDING, NOT GHOSTWRITING