Technology InteGrator and AcceleratoR (TIGAR)
ARPA-H is funding technology development to enable temperature-flexible storage and distribution of regenerative tissues, organs, and complex biologics, with proposals focused on deployable solutions rather than basic biology alone.
⚑ Federal contract solicitation, not a grant/assistance award. · Applicant restrictions apply; the notice does not identify universities as eligible direct applicants. · Proposals must include a deployment strategy for thick tissues; cellular-only solutions are not considered. · Solution video and full proposal deadlines were amended for intake Group 1; follow the latest ISO.
Unit fits — one characterization, each unit's own rules
| Tom Love Innovation Hub | 45 partial | funds applied research; prototyping/demonstration stage; deep-tech content |
| IPPRA | 15 none | university cannot apply directly (ineligible) |
| Physical Sciences & Engineering (demo) | 15 none | university cannot apply directly (ineligible) |
Description
Amendment 4 The ISO was updated to extend the Solution Video submission deadline to August 12, 2026 and the Full Proposal submission deadline to September 17, 2026 for intake Group 1. See page 3 of the full text ISO for more information. Amendment 3 (1) Appendix B was updated to remove track changes (2) Appendix C4 was updated to remove an erroneous comment. Amendment 2 (1) Instructions on how to submit a Solution Video were added to the ISO (see pages 7-8). (2) Information related to the Video Captions file was added to Appendix B.0 (Solution Video Format and Instructions). (3) The instructions in Appendix B.1 (Template for Supplemental Slides) were simplified, and a Cost Summary slide was added (see Slide 7). (4) Appendix C.3 was updated to reference "Phase" rather than "Year" for clarity. (5) The Administation and National Policy document in Appendix C.4 was replaced with an updated document. Amendment 1 The ISO was updated with the new webinar and webinar registration dates. Effort Description: TIGAR Exploratory Topic will forge entirely new paths to stabilizing regenerative tissues and organs by seeding the development of enabling technologies that can unlock temperature-flexible storage in increasingly larger and more complex biological systems. Solutions may involve any combination of new materials, artificial intelligence/machine learning, high-throughput screening methods, biological interventions, devices, processing methods, analytical technology, and packaging approaches that can overcome current roadblocks and yield a leap in the ability to store and distribute complex biologics, without introducing high cost or complexity. Strategies that reduce reliance on strictly controlled temperature zones and can ensure safe storage in a range of environmental conditions are preferred. While long-term temperature-flexible storage is ideal, any advance that removes logistical hurdles or establishes shelf-life stability at easy to maintain temperatures (preferably non-cryogenic) will be considered. Innovations at the cellular level without a strategy for deployment in thick tissues will not be considered. Please ensure to follow this opportunity for any updates. For more information on the TIGAR Exploratory Topic visit: https://arpa-h.gov/explore-funding/initiatives-and-sprints/tigar For information on Proposer's Day details and registration information, please see Special Notice ARPA-H-SN-26-142
Eligibility
Applicant restrictions (federal contract). Set-aside: No Set aside used. Notice type: Solicitation. Organization: HEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH / ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H).
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Proposal brief SEE AN EXAMPLE →
A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.
Proposal shell · HHS services agencies (SAMHSA / HRSA / CDC / ACF) conventions SEE AN HHS EXAMPLE →
Funder-faithful document skeletons — HHS services agencies (SAMHSA / HRSA / CDC / ACF)'s document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.