Office-Wide Innovative Solutions Opening for Proactive Health Office (PHO)
ARPA-H is seeking proposals from eligible non-federal entities for proactive health solutions that improve prevention, early detection, and system-level delivery of health-promoting interventions before disease or major quality-of-life decline occurs.
⚑ FFRDCs and government entities, including federal government employees, are not permitted to respond. · Submission is through the ARPA-H solutions portal; Grants.gov submission was removed. · Solution summary is required before proposal; cannot submit both at the same time. · Open until 2029-03-03.
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 65 good | technical depth: substantial; funds applied research |
| IPPRA | 58 good | portfolio topic: public_health (primary); signature methods: community engaged; social/behavioral work is substantial; funds applied research; university can only partner, not lead; biomedical core — IPPRA health lane is communication/crisis/policy (capped); clinical-trial/biomedical core — IPPRA angle is policy/community (capped) |
| Tom Love Innovation Hub | 45 partial | funds applied research; prototyping/demonstration stage; deep-tech content |
Description
The Proactive Health Office (PHO) at ARPA-H is seeking solutions to improve the healthspan and health outcomes of Americans prior to the onset of disease and/or the development of diminished quality of life from illness. Specifically, PHO hypothesizes that 1) population-level improvements in access to and uptake of disease prevention and wellness-promoting behaviors and 2) development of novel early-detection methods and prophylactic interventions could drastically improve the health of American throughout their lives, and 3) that system level innovations are required for delivery of proactive health effectively. Solution summary submissions must be submitted to: https://solutions.arpa-h.gov Questions must be submitted to: https://solutions.arpa-h.gov/Ask-A-Question/ Proposal submission should be submitted to: https://solutions.arpa-h.gov/Submit-Proposal/ Amendment 1 is effective immediately; however, if an entity has previously submitted a solution summary and/or a proposal, the base solicitation will be followed for those submissions. If a solution summary is submitted; however, a proposal has not been submitted yet, the proposal will be evaluated in accordance with this amendment. The amendment: Removes the option to submit a proposal through Grants.gov in Section 1 and Section 4.4. Removes the option for a proposer to submit a solution summary and proposal at the same time. Language is deleted in Section 2.2 and Section 5.1. Removes duplicative language about the type of eligible proposers in Section 3.1 because language is found in Section 2.2. Incorporates language in Section 3.2 to show “FFRDCs and government entities, including federal government employees, are not permitted to respond to this solicitation…” and includes information on how handle unique proposal situations. Incorporates language in Section 3.5 to encourage submission of research ideas notwithstanding any potential ARPA-H award limitations. Incorporates language in Section 4.1 to expand on the reasoning for requiring solution summaries. Incorporates language in Section 4.4 to clarify required documents for other transaction and cooperative agreement proposal submissions. Extends the solicitation to be open until March 3, 2029. Removes time limiting language in Section 4.5. Includes language in Section 4.6 to show, “ARPA-H is responsible for handling submissions to the extent permitted under applicable federal law, including the Freedom of Information Act (FOIA)” and adds language in Section 5.5 to include FOIA. Removes the Section 4 “Security Information” language which only referenced Section 6.1. Clarifies in Section 5.2, the Task Description Document and the Research Description Document will not be evaluated as part of the proposal evaluation process. Updates Criterion 4 under Section 5.2 to include “Budget Risk Analysis” instead of “Price Realism”. Includes requirements to comply with NIH’s Genomic Data Sharing Policy if applicable, in Section 6.1 Incorporates requirements for sans serif fonts to be used for readability purposes in Appendix A. Incorporates administrative changes. Incorporates administrative changes and updates language under Section 10 in the Administrative & National Policy Requirements Document Template in both Cooperative Agreement and Other Transaction Bundle. Incorporates an updated Model Cooperative Agreement and Model OT in the Cooperative Agreement and Other Transaction Bundle.
Eligibility
Applicant restrictions (federal contract). Set-aside: . Notice type: Solicitation. Organization: HEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH / ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H).
Apply
Proposal brief SEE AN EXAMPLE →
A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.
Proposal shell · HHS services agencies (SAMHSA / HRSA / CDC / ACF) conventions SEE AN HHS EXAMPLE →
Funder-faithful document skeletons — HHS services agencies (SAMHSA / HRSA / CDC / ACF)'s document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.