Resilient Systems Office (RSO) Mission Office Innovative Solutions Opening (ISO)
ARPA-H seeks solution summaries and proposals for projects that develop cutting-edge technologies to improve the quality, efficacy, and reliable availability of healthcare and public health services.
⚑ Federal contract solicitation; applicant restrictions not specified in notice text. · Solution summary required before proposal. · Amendment 2 updates proposal/attachment requirements and removed cooperative agreements as an award instrument. · Submissions via ARPA-H solutions portal; close date 2029-03-05.
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 80 strong | technical depth: substantial; funds applied research |
| IPPRA | 58 good | portfolio topic: public_health (primary); social/behavioral work is minor; funds applied research; biomedical core — IPPRA health lane is communication/crisis/policy (capped) |
| Tom Love Innovation Hub | 45 partial | funds applied research; prototyping/demonstration stage; deep-tech content |
Description
This ISO seeks solution summary and proposal submissions for projects that fall within the scope of the ARPA-H mission Resilient Systems Office (RSO). RSO’s interest areas will address systemic challenges across the healthcare and public health landscape by investing in cutting-edge technologies that address long-standing gaps in the quality, efficacy, and consistent availability of care. Solution summary submissions must be submitted to: https://solutions.arpa-h.gov Questions must be submitted to: https://solutions.arpa-h.gov/Ask-A-Question/ Proposal submission should be submitted to: https://solutions.arpa-h.gov/Submit-Proposal/ Amendment 2 is effective immediately; however, if an entity has previously submitted a solution summary and/or a proposal, the base solicitation will be followed for those submissions. If a solution summary is submitted; however, a proposal has not been submitted yet, the proposal will be evaluated in accordance with this amendment. The amendment: Updated solutions summary template; Updated bundle of attachments for other transactions (admin & national policy requirements document, cost proposal narrative, cost proposal workbook, task description document, and technical & management proposal) for proposal submissions; Removed cooperative agreements as a potential award instrument and removed bundle of attachments for cooperative agreements; Updated various sections of the ISO.
Eligibility
Applicant restrictions (federal contract). Set-aside: . Notice type: Solicitation. Organization: HEALTH AND HUMAN SERVICES, DEPARTMENT OF / NATIONAL INSTITUTES OF HEALTH / ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H).
Apply
Proposal brief SEE AN EXAMPLE →
A one-page internal memo: fit assessment, submission requirements, document scaffold, and next steps dated back from the deadline — tailored to your project idea if you add one.
Proposal shell · HHS services agencies (SAMHSA / HRSA / CDC / ACF) conventions SEE AN HHS EXAMPLE →
Funder-faithful document skeletons — HHS services agencies (SAMHSA / HRSA / CDC / ACF)'s document set with section headings, page limits, reviewer guidance, and writing prompts; add a project idea to get [DRAFT] starter bullets. Download as .md for Word or Overleaf.