BARDA DRIVe EZ-BAA (EZBAA - 22-100-SOL-00003)
BARDA’s EZ-BAA funds proposals that develop advanced medical countermeasure and biodefense-related technologies, platforms, diagnostics, vaccines, and response tools under specific areas of interest.
⚑ federal contract solicitation / BAA-style mechanism · topic-specific areas of interest with separate closing dates · BARDA medical countermeasure focus; proposal must align to an open AOI · eligibility and submission rules are controlled by the posted solicitation/amendments
This is a BARDA applied-biomedical and clinical countermeasure/diagnostics opportunity, centered on therapeutics, vaccines, and lab/host-based medical technologies. IPPRA’s team works on public risk perception, warning communication, and policy around climate, energy, and hazards, so this is outside their program and not something they would typically pursue with a PI from this roster.
JUDGED AGAINST THE ROSTER'S PUBLICATION DOSSIER · GPT-5.4-MINI · 2026-07-07
Unit fits — one characterization, each unit's own rules
| Physical Sciences & Engineering (demo) | 80 strong | technical depth: substantial; funds applied research |
| IPPRA | 58 good | peripheral portfolio topic: public_health; social/behavioral work is minor; funds applied research; biomedical core — IPPRA health lane is communication/crisis/policy (capped) |
| Tom Love Innovation Hub | 45 partial | funds applied research; prototyping/demonstration stage; deep-tech content |
Description
This announcement serves as a reissuance of the BARDA DRIVe EZ-BAA, now known as EZ-BAA-22-100-SOL-00003. This announcement hereby supersedes and replaces prior iterations of the BARDA DRIVe EZ-BAA (e.g. BAA-20-100-SOL-0002). Please reference the attached announcement and applicable amendments for specifics. Additionally, please visit https://drive.hhs.gov/. _______ Amendment 001: This amendment to the EZBAA hereby opens the following research areas of interest ("AOI"). Please review the amendment for details of each AOI, including closing dates: AOI #15: ReDIRECT AOI #16: Lab at Home AOI #17: Digital MCMs AOI #18: Host-Directed Therapeutics AOI #19: Healing Lungs AOI #20: DRIVe Forward AOI #21: Vaccines on Demand AOI #22: ReBooT AOI #23: Host-Based Diagnostics _____ 11/8/22 - Please see Amendment 002 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Adding the the following Area of Interest (AOI): AOI #24: REPAIR 2. Clarifying an adminstrative error. _____ 11/14/22 - Please see Amendment 003 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Revising the following Area of Interest (AOI): AOI #19: Healing Lungs _____ 12/15/22 - Please see Amendment 004 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): AOI #21: Vaccines on Demand ______ 1/11/23 - Please see Amendment 005 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Pausing the following Area of Interest (AOI) by establishing a new closing date of February 15, 2023 at 12:00PM ET: AOI #15: ReDIRECT ______ 2/1/23 - Please see Amendment 006 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): AOI #19: Healing Lungs 2. Updating the closing date for the following Area of Interest (AOI): AOI #17: Digital MCMs 3. Updating the closing date for the following Area of Interest (AOI): AOI #16: Lab at Home 4. Revising the following Area of Interest (AOI): AOI #16: Lab at Home ______ 2/3/23 - Please see Amendment 007 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): AOI #24: REPAIR ______ 5/1/23 - Please see Amendment 008 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Adding the following Area of Interest (AOI): AOI #25: FASTx 2. Updating the language in Section III (F) of the Easy Broad Agency Announcement titled “Plus (+) Phase”. ______ 5/18/23 - Please see Amendment 009 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Reopening the following Area of Interest (AOI), which is reopened to support project Next Gen: AOI #21: Vaccines on Demand ______ 5/25/23 - Please see Amendment 010 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Revising the following Area of Interest (AOI): AOI #24: REPAIR 2. Updating the closing date for the following Area of Interest (AOI): AOI #24: REPAIR ______ 6/27/23 - Please see Amendment 011 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Closing the following Area of Interest (AOI): AOI #18: Host-Directed Therapeutics 2. Closing the following Area of Interest (AOI): AOI #23: Host-Based Diagnostics 3. Updating the closing date for the following Area of Interest (AOI): AOI #19: Healing Lungs ______ 9/13/23 - Please see Amendment 012 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): AOI #16: Lab at Home 2. Updating the closing date for the following Area of Interest (AOI): AOI #17: Digital MCMs 3. Updating the closing date for the following Area of Interest (AOI): AOI #19: Healing Lungs 4. Revising the following Area of Interest (AOI): AOI #16 Lab at Home 5. Adding the following Area of Interest (AOI): AOI #26: Agnostic Diagnostic _______ 9/14/23 - Please see Amendment 013 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Pausing the following Area of Interest (AOI): AOI #20: DRIVe Forward ________ 9/26/23 - Please see Amendment 014 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Pausing the following Area of Interest (AOI): AOI #21: Vaccines on Demand _________ 10/26/23 - Please see Amendment 015 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Updating the closing date for the following Area of Interest (AOI): AOI #22: ReBoot 2. Updating the closing date for the following Area of Interest (AOI): AOI #25: FASTx 3. Revising the following Area of Interest (AOI): AOI #22: ReBoot 4. Revising the following Area of Interest (AOI): AOI #25: FASTx ___________ 10/30/23 - Please see Amendment 016 for Easy Broad Agency Announcement (EZ-BAA) EZ-BAA-22-100-SOL-00003. Under this Amendment, BARDA is: 1. Pausing the following Area of Interest (AOI): AOI #24: REPAIR __________
Eligibility
Applicant restrictions (federal contract). Set-aside: . Notice type: Solicitation. Organization: HEALTH AND HUMAN SERVICES, DEPARTMENT OF / OFFICE OF ASSISTANT SECRETARY FOR PREPAREDNESS AND RESPONSE / BARDA - ASPR / DAAPPO / BARDA DCMA.
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