DoW Alzheimer’s Transforming Research Award
The FY26 DoD Alzheimer’s Transforming Research Award funds non-incremental research to identify or validate AD/ADRD risk or protective factors and to develop risk-reduction or prevention solutions, with clinical research allowed but no clinical trials or animal research.
⚑ Preliminary data required · Community collaboration required for prospectively enrolling human subjects · Clinical trials prohibited · Animal research prohibited
Unit fits — one characterization, each unit's own rules
| IPPRA | 84 strong | portfolio topics: public_health, mental_behavioral_health; social/behavioral work is substantial; funds applied research |
| Physical Sciences & Engineering (demo) | 80 strong | technical depth: substantial; funds applied research |
| Tom Love Innovation Hub | 30 weak | funds applied research; deep-tech content |
Description
Summary: The fiscal year 2026 (FY26) Alzheimer’s Research Program (AZRP) Transforming Research Award (TrRA) supports non-incremental, robust, well-designed research that drives transformative advancements in reducing risk and preventing the development of Alzheimer’s disease and/or Alzheimer's disease related dementias (AD/ADRD).
Distinctive Features:
• Applications must address at least one of the following focus areas:
○ Risk Factor Knowledge: Research that advances understanding, identification, and/or validation of risk and/or protective factors, with research outcomes/products focused on accelerating solutions. Projects may include, but are not limited to, research on environmental, epigenetic, genetic, lifestyle, occupational, or other risks not listed here.
○ Risk Reduction Solutions: Research that describes methods, technologies, and strategies that contribute to reducing risk and preventing AD/ADRD.
• Clinical research is allowed, however clinical trials and animal research are prohibited.
• Preliminary data are required.
• Community collaboration is required for research prospectively enrolling human subjects.
• Career Initiation or Transition (CIT) Partnership Option: The TrRA includes an option for more than one PI and supports both new and existing collaborative partnerships. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). If utilizing this option, at least one independent investigator must meet
Apply
View on Grants.gov → CONTACT: JoAnn Martin Grantor <help@eBRAP.org>